Abstract: With the popularization and application of large mining height fully mechanized mining technology, the production efficiency and mechanization level of coal have been continuously improved, but the dust pollution problem of working face has become increasingly prominent. In order to effectively solve the dust pollution problem of the fully mechanized working face with large mining height, the 85219 fully mechanized mining face of Sandaogou Coal Mine is taken as the research object, aiming at the dust characteristics of the coal mining, support moving, roadway and transfer point areas, the comprehensive prevention and control technology system of “internal and external spray + support dust collection + dust source tracking” and the comprehensive dust prevention intelligent monitoring platform of the mine are built to realize the remote monitoring and intelligent control of coal mine dust. The research and application results show that after the comprehensive prevention and control technology system is adopted in the coal mining and support moving area, the total dust concentration at each measuring point of the fully mechanized mining face is lower than the threshold of 20 mg/m³, and the dust removal efficiency can reach more than 90%. The respirable dust concentration is lower than 10 mg/m³, and the dust removal efficiency reaches about 85%. The mine comprehensive dust prevention intelligent monitoring platform used in the roadway and transfer point area not only monitors the dust concentration of the working face online, but also the dust removal device can automatically spray dust removal according to the actual situation on site. The dust removal efficiencies of both total dust and respirable dust at each measuring point are more than 80%. Combining the comprehensive control technology system of “internal and external spray + support dust collection + dust source tracking” with the comprehensive dust prevention intelligent monitoring platform of the mine can effectively reduce the dust concentration of fully mechanized mining face, improve the dust removal efficiency while realizing intelligence, effectively improve the working face environment, and provide guidance and reference for the development of effective dust removal measures in mining areas.