Abstract: Taking Shanghengshan multilayer and containing Vanadium shale Deposit as subjects,Study the stress distribution characteristics of strike-drift and its destress methods in sublevel-alternation subsequent filling stoping. Using the Phase² to simulate stress and offset changes of strike-drift with 10 time steps of stage mining. In panel stoping,wall rock stress of strike-drift under stoping are higher than other regions 3. 19%（average）; high stress state are focused on tunnel roof and floor,the range are 51. 61% ~ 58. 14% and 26. 19% ~ 54. 54% respectively. Design depressurised-borehole and short depressurised-lane to alleviate this problem,arrange drill hole along the inclination and vertical orebody dip,short lane near and far from orebody in the side. Tunnel in high stress area are decreased 56. 86%,56. 27%,47. 48% and 7. 03% respectiveIy（average）,with its stability ensured。In the condition of high stress drift of pressure relief,should make the depressurised-borehole along the inclined arrangement and short depressurised-lane near the side wall layout,reduce the tunnel with high stress zone. The results can provide reliable basis and useful references for actual mining.