Abstract: The traditional geological survey which involved in single discipline and non-integral field work could not meet the demands of development of green mining industry and ecological civilization construction.It is imperative to alter the manners of resource exploration, and carry out a multi-discipline comprehensive geological investigation and evaluation.This paper takes non-ferrous mineral resource base in eastern Tianshan mountains in Xinjiang as the research case.The evaluation indexes are preferentially selected respectively from resource conditions, techno-economic conditions and geological environmental conditions, and the evaluation index system is constructed via analytic hierarchy process.Finally, fuzzy comprehensive evaluation method is adopt to techno-economic comprehensive evaluation of ore resources in the base.