Abstract: Well SK-2 has the important value for deep geological scientific research,which is the first coring hole of drilling through the Cretaceous terrestrial in the world.According to the management and protection conditions of cores in well SK-2, on the basis of the field site environment and the long-term preservation technology status, professionals have shaped the technical methods and protective measures for cores in well SK-2.The protection methods have very strong practicability and demonstration basis for being applied in practical work, and the social effects in the process of core receiving and protection.They can be widely promoted and applied in the management and protection of the physical geological data in China.