Abstract: Aiming at the problem that the separate optimization of pit boundary and mining-stripping plan for open-pit mine is not the global optimal solution,the simultaneous optimization method of pit boundary and mining-stripping plan was put forward.A series of optimal geological candidates pit boundary were constructed by the conditions of the given surface constraints,slope angle constraint,total exploitation,boundary increment and so on,and then the mining-stripping plan of each candidate pit boundary was optimized.With the maximum NPV as the objective function,the optimal boundary of simultaneous optimization for pit boundary and mining-stripping plan was obtained.By establishing the surface elevation model and the numerical model of the deposit,and setting up the slope angle and the technical and economic parameter constraints,separate optimization method and simultaneous optimization method of pit boundary and mining-stripping plan were respectively used in the open-pit iron mine.When separately optimized,the NPV of optimal pit boundary is 2.58 billion yuan,and when simultaneously optimized,the NPV of optimal pit boundary is 4.57 billion yuan,and the NPV of profit is increased by 1.99 billion yuan.The results show that the simultaneous optimization is better than the separate optimization,which can provide favorable means and reliable references for the decision makers of open-pit production.