Abstract: In order to study the mass disposal technology of copper nickel water quenched smelting slag from a copper nickel mine and explore the feasibility and technology of preparing filling cementitious material based on copper nickel water quenched smelting slag, this study carried out grinding test and laser particle size analysis of smelting slag, orthogonal test of alkali activated cementitious material ratio based on smelting slag, uniaxial compressive strength test of filling sample, filling sample and cementitious material The results show that:the pozzolanic activity of the copper nickel water quenched slag produced by the copper nickel mine smelter is low, and the alkali activator prepared in the laboratory has no obvious effect on the activation of the copper nickel water quenched slag.In the preparation of filling cementitious materials, copper nickel water quenched smelting slag is activated by alkali, the optimal grinding time of the slag is 50 min, and the D(0.5) is 28 μm.In the alkaline filling slurry with ordinary Portland cement as the main cementitious material, the addition of smelting slag results in the increase of ettringite production.With the decrease of the particle size of grinding smelting slag, the corrosion phenomenon on the surface of smelting slag particle becomes more and more obvious.