Abstract: The limestone mine of Tanjiashan cement in Bazhong, Sichuan province is divided into east and west mining areas.As the first stage of mining, the eastern part has a designed slope height of about 300 m, and the final overall slope angle is about 41.9°.The geological conditions of the mine are complex, the bedding plane in steep dip and monocline, the rock mass joints are developed, and there are karst caves with different scales underground.The slope is a typical high slope of steep dip and bedding open-pit mine, and the potential safety hazard is relatively prominent.Based on the field geological survey, the possible failure modes of the limestone open pit slope in Tanjiashan are analyzed firstly by using the engineering geological analysis method, and the results show that there are hidden dangers of different failure modes in the overall slope and the bench slope.Secondly, considering the blasting and the possible distribution of underground karst cave, the possible danger of slope safety in the production process are pointed out in detail.Finally, according to the potential danger of slope safety, the corresponding countermeasures are put forward.The research results can provide a reference for mine production and safety management.