Abstract: The karst ground collapse disaster has the characteristics of concealment, suddenness, heterogeneity and multi-factors.In order to divide the susceptibility of karst ground collapse disasters truly and accurately, this paper establishes an analytic hierarchy process-fuzzy comprehensive evaluation (AHP-FCE) model based on the analytic hierarchy process and fuzzy mathematics theory.After analyzing the disaster-causing factors of karst ground collapse, 6 condition layers and 15 influencing factors are selected, and the weights are determined according to the importance, and the susceptibility is evaluated according to the principle of maximum membership.Finally, based on the AHP-FCE model and using Python language, a zoning evaluation system for the susceptibility of karst ground collapse disasters is developed, thereby simplifying the calculation process.In order to verify the accuracy of the model, a school in Shenzhen and the surrounding karst ground collapse hazard susceptibility is evaluated, and the result is Class Ⅱ(medium susceptibility level), which is consistent with the actual situation and proved that the method is correct and effective.