Abstract: For the purpose of solving the problem that the waste water produced by a tungsten-molybdenum enterprise in the process of tungsten-molybdenum separation is difficult to reuse to the tungsten selection section, sodium hypochlorite oxidation technology, Fenton advanced oxidation technology and ozone advanced oxidation technology are used to treat the tailings reservoir wastewater, and some of them are degraded COD, the effect of comparing the wastewater treated by ozone advanced oxidation technology on tungsten selection. The results show that the reuse of waste water treated by ozone advanced oxidation technology has no effect on the mineral processing index. The waste water of tailings reservoir treated by ozone advanced oxidation technology replaces or partially replaces the new water, thus reducing the water storage pressure of tailings reservoir and the recycling of water resources, so as to achieve the purpose of saving water and discharging.