High pressure grinding rolls is a kind of high-efficiency crushing equipment, which has been widely used in the field of iron ore processing, and has a good effect in the separation of low-grade iron ore when combined with pre tailing process.With the increase of attention to it, high pressure grinding rolls has also been gradually applied to non-ferrous metal mines in recent years.Based on the structure and working principle of high pressure grinding rolls and combined with the application examples of high pressure grinding rolls in non-ferrous metal mines and the research on the influence of high pressure grinding rolls technology on subsequent beneficiation operations, the advantages of high pressure grinding rolls in non-ferrous metal beneficiation are systematically expounded in this paper.At the same time, the applicable conditions of high pressure grinding rolls and semi-autogenous grinding technology in non-ferrous metal beneficiation are pointed out.This paper briefly introduces the selection basis and application examples of three comminution processes in non-ferrous metal mines that open-circuit crushing, semi-closed-circuit crushing of side material return and full-closed-circuit crushing of screening.At the same time, combined with the application of high pressure grinding rolls ultra-fine crushing-pre-separation process in the beneficiation of low-grade iron ore, a prospect is made for the application of the combined process of high pressure grinding rolls and coarse-grained tail throwing technology in the low grade non-ferrous metal ore resources.