Abstract: As a development mode of coal mining enterprises, coal mine trusteeship mode is becoming more and more mature in the development process of coal mining enterprises in China. The coal mine trusteeship mode is in a new stage in southwest region in China, and there is a significant transition phase with the trusteeship mode of the coal mining enterprises in northern region. In order to adapt to the development needs of the coal industry under the new situation, make full use of the coal resources in Guiyang City, and do a good job in the supply-side reform of the coal industry, according to the arrangements of the Guiyang Municipal Party Committee and the Municipal Government, Guiyang Mineral Energy Investment Group Co., Ltd. proposes to integrate the small and medium-sized coal mining enterprises in Guiyang City by using the coal industry association as the trusteeship mode of coal mining enterprises. The association trusteeship mode has effectively solved the problem of coal resource utilization and market demand, and have established the communication channel between enterprises and government. At the same time, the association trusteeship mode fills up the excessive application of coal mine trusteeship in Guiyang City, and has a more flexible management mode, which is conducive to the formation of a good cycle for the government, coal mining enterprises, market demand enterprises and service enterprises, and is conducive to promoting the development of the industry. Through the application of the association trusteeship mode of the small and medium-sized coal mine in Guiyang City, it provides suggestions for the development of coal mine trusteeship in other provinces and cities in the southwest region.