Abstract: Heat hazard in deep mine is increasingly prominent, which seriously threatens the life and health of operators and further affects the production efficiency of mine. Variation rule of surrounding rock temperature with radial depth in air inlet laneway of 2102 working face, 3100 working face, 3106 working face and 3107 working face in Menkeqing Coal Mine is measured by experimental method of drilling in surrounding rock; based on ANSYS software, the cooperative heat insulation effect of expansion vitrified microbeads cement insulation material and air sandwich is studied. The results show that the relationship between surrounding rock temperature and radial depth conforms to ExpAssoc model and the correlation coefficient R² is 0.991 06. When the thickness of expansion vitrefied microbeads cement heat insulation material and air interlayers are 3 cm, 6 cm, 9 cm, 12 cm, 15 cm and18 cm, the material-air collaborative heat insulation sequence is higher than that of air-material collaborative heat insulation sequence, the original laneway wall temperature is higher, the heat control circle radius is smaller, and the heat insulation effect is better. In the case of material-air collaborative heat insulation, the thickness of air layer within 12 cm has a greater effect on the heat insulation effect, and the thickness of material layer within 6-18 cm has a greater effect on the heat insulation effect. The convective heat transfer coefficient is inversely proportional to the thickness of the heat insulation layer. The thickness of the air layer varies greatly within 12 cm, but is less affected by the thickness of the material layer. The research results can provide reference for multi-layer heat insulation and cooling in mine.