Abstract: Surface river seepage water in non-metallic mines will affect mine safety, the physical detection methods often use in engineering to determine the approximate location of the seepage water river section, but a single physical exploration method positioning error is large. In order to solve the problem of large positioning error, this paper takes the seepage water river section of a phosphorus mine in Guizhou as the research object, and proposes to use the flow section method and the ground-penetrating radar method to carry out comprehensive detection of the seepage water river section. The results show that according to the measurement results of LS300-A flow meter, the seepage situation of different sections of Yangshui River is obtained: the permeability from upstream to downstream of Dashitou is the strongest, followed by the section from the outlet of culvert （I） to the groundwater environmental monitoring well, and the weakest one is from the explosives depot to the downstream of the explosives depot; using ground-penetrating radar to determine the distribution of undesirable geologic bodies of the leakage section of the river, and analyzing the abnormal areas of the georadar image, it is concluded that each seepage section has a fissure zone development. There are fissure zone development, among which, the fissure development degree of the section from the outlet of culvert （I） to the groundwater environment monitoring well is higher than that of the upstream and downstream of the explosives depot. Compared with the traditional single geophysical method, the method adopted in this study overcomes the limitations of a single geophysical field in exploration, effectively improves the accuracy of the exploration results, and has certain practical significance in guiding the detection of seepage water in surface rivers of non-metallic mines and the safe exploitation of mining resources.