Abstract: The stability of the mining slope decreases year by year with the extension of the lower mining, and its stability is closely related to the mining operation. To ensure the safety of mining operations, reinforcement measures of anchor（pole） cables + frame beams are adopted for the formed mining slope. The selection and optimization of reinforcement structural parameters are related to mine safety and sustainable development. The optimization and effectiveness evaluation of slope reinforcement parameters in mining areas have become a hot research topic. Using drones to survey the terrain of the mining slope, a real three-dimensional model of the mining slope is established based on the terrain survey data. The structural parameters for reinforcing mining slopes with different rock mass structures are analyzed, including the anchorage length of anchor cables, the spacing between frame beams, and the width of the platform. The optimization parameters for different rock mass structure types are determined based on numerical simulation results. The results show that when the length of the anchor cables increases from 8 m to 12 m, the displacement of the slope decreases by 20.5%, and the maximum axial force of the anchor cable does not change significantly. Increase the spacing between frame beams to 4 m×4 m and 5 m×6 m, the safety factor decreased by 7.6% and 3.8% respectively, with the latter having the smallest slope displacement value. From a safety factor perspective, a 12 m wide platform is more reasonable. By setting up anchor cable stress monitoring points in representative areas to monitor and evaluate the stress and stability of the mining slope, the evaluation results show that using optimized anchorage parameters for the mining slope is reasonable and can guide the selection of reinforcement parameters for the lower mining area, providing reference for similar mining slope protection.