Abstract: A graphite-vanadium ore is from a foreign country, the fixed carbon content of the raw ore is 15.30%, with the V₂O₅ content of 0.51%, the graphite ore is mainly recovered ore, and accompanying the recovery of vanadium-containing mineral, which is roscoelite, the dissemination of graphite is coarse, and the dissemination of roscoelite is fine. The separation tests are carried out about graphite flotation-roscoelite flotation for the raw ore, the suitable separation parameters of graphite separation are obtained: the grinding fineness of rougher is −0.074 mm 52.66%, the collector of graphite is the mixture oil of kerosene∶paraffin oil=1∶1, and the dosage is 70 g/t for rougher with the water glass of 1 500 g/t, the regrinding fineness of rougher concentrate is −0.074 mm 60.04%. And the suitable separation parameters of roscoelite separation are obtained too. The collector of roscoelite is P8X with the dosage of 200 g/t, the grinding fineness of rougher concentrate is −0.074 mm 74.35%. The closed-circuit test is carried out with the testing procedures of one roughing, three scavenging and four cleaning graphite flotation-one roughing, two scavenging and two cleaning roscoelite flotation, and the separation indexes can be obtained, the fixed carbon content of graphite concentrate is 96.63% with the recovery rate of 96.28%, and the V₂O₅ content of roscoelite concentrate is 1.86% with the recovery rate of 83.41%, the research results provide a technical reference for the comprehensive recovery of this type of graphite-vanadium ore.