Abstract: In response to the technical challenge of insufficient silver recovery efficiency in lead-zinc-silver concentrate, and the inability to efficiently recover and utilize valuable elements such as lead, zinc, and sulfur, in this paper, the technology of pre-flotation of silver, lead and zinc, recovery of lead and zinc by direct cyanidation-cyanidation tailing flotation, high cyanide leaching of lead and zinc concentrate and low cyanide leaching of lead and zinc tailings-cyanidation tailing flotation of sulfur concentrate are studied. The results show that the integrated method of technology for flotation of lead-zinc concentrate by primary cyanide and sulfur suppression, high cyanide leaching of silver for secondary lead-zinc concentrate, low cyanide leaching of silver for tertiary lead-zinc tailings and activation of flotation of sulfur concentrate by tertiary cyanide tailings is adopted, the optimum technical parameters are as follows: the first grade technical conditions are: grinding fineness −0.074 mm accounting for 90%, dosage of sodium carbonate 2 000 g/t, dosage of sodium cyanide 2 000 g/t, cyanide inhibition time 60 min, the concentration of ore is 28%, the dosage of collector is 200 g/t, the flotation time is 15 min, the flotation process of primary roughing and secondary cleaning is once roughing and once cleaning, the secondary technical conditions are 33% concentration of ore, 0.80%-1.00% concentration of sodium cyanide, once leaching for 36 h, the concentration of sodium cyanide is 33%, the concentration of sodium cyanide is 0.80%-1.00%, after one leaching, the ore is ground twice with hydrogen peroxide as leaching aid, the grinding fineness is −0.037 mm accounting for 95%, the concentration of sodium cyanide is 0.80%-1.00%, the second leaching is 24 hours, the three-stage technical conditions are grinding fineness −0.037 mm accounting for 90%, the concentration of ore is 33%, the concentration of ore is 100%, the concentration of ore is 100% and the concentration of ore is 100%, the concentration of sodium cyanide is 0.15%-0.20%, the leaching time is 24 h, the four-stage technical condition is 33%, the pH value of pulp is adjusted to 4 by sulfuric acid, the stirring time is 60 min, the pH value is adjusted to 6 by sodium carbonate, the stirring time is 10 min, the dosage of collector is 600 g/t, the floatation time is 20 minutes, and the floatation process is one roughing and one sweeping. The comprehensive recovery rates of silver, lead, zinc and sulfur in the lead-zinc-silver concentrate are 92.71%, 90.78%, 94.92% and 93.66% respectively, it realizes the high value and resource utilization of lead-zinc-silver concentrate, and provides an effective technical method for the treatment of this kind of lead-zinc-silver concentrate.