Abstract: To study the seepage-stress-damage mechanism in the grouting process of the water-rich coal seam, take the grouting reconstruction project of the vice-mine in the No. 2 water-rich coal seam of the Balasu Coal Mine as an example. Based on the damage model of the coal rock, according to the shear slip and dilatancy effect of fractures under the action of seepage pressure, the seepage-stress-damage coupling numerical model is established. The effects of grouting rate and grout viscosity on the stress field, seepage pressure, and damage to water-rich coal seams are analyzed. The results show that the grouting rate and grout viscosity have significant effects on the stress field, seepage pressure, and damage to the coal seam. The grouting rate increases from 0.3 cm/s to 0.9 cm/s led to the stress, seepage pressure, and damage area increasing by 3, 1.5, and 30 times, respectively. The increase in grout viscosity leads to a higher stress concentration at the fracture tip, while the high seepage pressure zone of the coal seam decreases. There is no new damage zone generated, but there is further expansion of the original damage. Increasing the grouting rate and grout viscosity is beneficial for crack expansion and grout diffusion. Due to the influence of high viscous resistance and low permeability on diffusion, the grouting rate should be the main factor in determining the grouting parameters. For the No. 2 water-rich coal seam of the Balasu Coal Mine, the maximum seepage pressure during grouting should not exceed 11.08 MPa.