Abstract: To solve the problem of low electrical resistivity interference in the application of multi-electrode resistivity method in the investigation of hidden disaster water factors in metal mines, taking the water seepage detection and treatment project of a metal mine in the Xiaoxing’anling Area as an example, multi-electrode resistivity method is used to search for areas with electrical anomalies. Drilling, metal mineral content testing, pumping tests, and other work are gradually carried out to eliminate low electrical resistivity interference caused by metal minerals, divide permeable areas, and verify the detection results of the permeable areas through on-site water seepage investigation and three-dimensional model water seepage calculation. The results show that the overall low electrical resistance of the multi-electrode resistivity method detection area may be related to its metal mineral content, but there is no significant difference in the metal mineral content between different areas, and local resistivity anomalies are not related to differences in metal mineral content. The permeability and water yield of the rock and soil mass in the low resistivity anomaly area are different from those in the surrounding area, indicating that it is a seepage channel for underground water inside the diversion dike to the outside of the diversion dike. The permeability calculated by establishing a model using permeable channels is basically consistent with the water yield obtained from on-site investigations, further verifying the reliability of multi-electrode resistivity detection results. Based on the above results, a permeability stability evaluation is carried out, and a seepage channel treatment plan is proposed and implemented, ultimately achieving effective treatment of seepage channels. The research results confirm that multi-electrode resistivity methods can effectively detect water infiltration channels in metal mines by eliminating the interference of low resistivity in metal mines.