Abstract: The dynamic seismic analysis of a high tailings dam is carried out using the time history method by selecting 2 measured seismic waves and 1 standard spectral fitting artificial seismic wave. The acceleration response, liquefaction zone distribution, earthquake permanent deformation, and dynamic stability of tailings pond under three different earthquake wave effects are studied. The research has shows that under earthquake action, the maximum acceleration of the tailings dam occurred at the initial dam crest, accumulation dam crest and slope area, and there is no dynamic response “whiplash effect” on the dam body. The liquefaction zone of the dam body mainly occurred in the shallow areas of sedimentary beaches. After the earthquake, the dam body showed overall seismic subsidence, accounting for approximately 0.18% of the dam height. The minimum safety factor of the dam under different earthquake waves is 1.51, which is greater than the minimum safety factor recommended by the specifications. Through dynamic seismic analysis, it is demonstrated that the safety of tailings ponds meets regulatory requirements, which can also provide reference for similar projects.