Abstract: Mining disturbance characteristics are closely related to the mining process, which is a typical irreversible nonlinear process. Under the influence of high stress and other complex geological environment, the mechanism of this nonlinear disturbance process is more complex, and the disaster problems induced are more prominent, which seriously restricts the mining of the deep ore body of a mine in northeast Yunnan Province. High ground stress and strong mining disturbance are the main causes of rockburst and other dynamic disaster causes. In order to ensure the safe and efficient mining of mineral resources in the deep part of this mine, firstly, this study analyses and inverts the deep three-dimensional stress field of the mine through the deep in-situ geostress measurement data. Secondly, a high-precision 3D simulation model is constructed by relying on Map3D boundary element simulation software, which is used for deep mining simulation and overall planning research of the ore body to be mined, based on the deep mining plan, rock mass mechanical parameters, engineering geological structure and stress environment. Through systematic numerical simulation and discussion, the following conclusions are drawn. The current mining scheme of this mine is deemed reasonable, the stress environment disturbance generated after the shallow ore body is mined out does not affect the deep ore body, and there is no risk of cross-disturbance between the mechanical environment of the area where the deep ore body is located and the shallow part; the results show that there are three kinds of mining directions, namely along the strike of the ore body, perpendicular to the strike of the ore body, and along the maximum principal stress, and the results show that there are three kinds of mining directions along the maximum principal stress program, the results show that along the maximum principal stress program is optimal, followed by vertical ore body strike program, but the difference between the two is not large, the site can also be implemented in accordance with the vertical ore body strike program, the program also has a certain improvement in the control of rock explosion disaster; more than one section of the simultaneous mining, with the progresses of mining, the stress concentration range is gradually expanding the internal corners of the ore body filler easy to be damaged and there is a risk of rockburst disaster in local hard rock mass on the periphery. The results of this study can provide references for the planning of deep mining scheme of similar mines in China.