Abstract: This paper focuses on the safe and efficient mining methods for gently inclined medium thick ore bodies. Based on the characteristics of this type of ore body, this paper first analyzes the current mining situation, and then summarizes the significance of safe and efficient mining methods in mining. This paper focuses on the key points of mining equipment selection and configuration, optimization of mining process parameters, roof management and support technology, as well as ventilation and dust prevention measures. Through in-depth analysis of these technical details, the aim is to provide scientific guidance and practical suggestions for safe and efficient mining of gently inclined medium thick ore bodies.