Abstract: Studying the distribution characteristics of in-situ stress is one of the basic paths to safe and efficient mining in mines. Aiming at the problem of in-situ stress distribution law in the North No.1 Mining Area of Shilu Iron Mine. The in-situ stress test device of instantaneous continuous hollow inclusion is adopted by the stress relief method combined with double temperature compensation. In-situ stress measurements are conducted at five locations within the North No.1 Mining Area of Shilu Iron Mine at levels −75 m, −90 m, and −105 m. Analysis of in-situ stress distribution in the North No.1 Mining Area of Shilu Iron Mine. The results show that the in-situ stress field of 220−250 m buried depth in the North No.1 Mining Area of Shilu Iron Mine is dominated by horizontal tectonic stress. At each measuring point, there are two principal stresses that are nearly horizontal, with their dip angles ranging from 1° to 29°. A principal stress is nearly vertical, with an angle of less than 30° from the vertical direction. The maximum principal stress at the five measurement points is oriented in the near-horizontal direction. The orientation of the maximum horizontal principal stress at each measurement point is variable, with the direction ranging from −70° to 110°. The direction of the maximum principal stress at each measurement point closely aligns with the distribution range of the maximum principal stress direction within the regional tectonic stress field. The maximum horizontal principal stress ranges from 6.80 to 11.93 MPa, categorized as low to moderate stress levels. σ_H, σ_h, and σ_v values escalate with increasing burial depth. The in-situ stress characteristic parameters K_Hv, K_Hh, K_av, and μ_m exhibit ranges of 1.35 to 2.46, 1.15 to 2.47, 1.14 to 2.30, and 0.07 to 0.42, respectively. This study offers crucial foundational data for safety operations, roadway stabilization, and stope design within the North No.1 Mining Area of Shilu Iron Mine.