Abstract: The old seismic data of sandstone type uranium deposits in the southwest of the Songliao Basin are limited by acquisition technology and complex surface structures. The original data has developed interference waves, severe high-frequency absorption, and weak effective wave signals. In addition, the data processing methods and technologies at that time are limited, resulting in the inability of the final result profile to meet the current requirements for continuous interpretation. This paper analyzes the characteristics of old seismic data from sandstone type uranium mines, and adopts targeted key technologies such as pre-stack comprehensive denoising, amplitude compensation, series deconvolution, and post stack frequency extension for processing. A low signal-to-noise ratio and low coverage seismic data processing flow is established. The results show that the resolution and signal-to-noise ratio of the reprocessed seismic data are significantly improved, and the interpretability of the data is enhanced, laying a good data foundation for the continuous interpretation work.