Abstract: A primary gold ore with finely disseminated high-arsenic and sulfur content, grading 4.38 g/t Au, 22.2 g/t Ag, 2.88% S, and 3.78% C, is subjected to process mineralogy analysis, revealing that gold primarily exists as exposed gold and sulfide-encapsulated gold. Knelson gravity concentration and flotation recovery tests are conducted on the ore. The results demonstrate that Knelson gravity concentration failed to effectively enrich gold, yielding a gold recovery rate of merely 5%-10% in the concentrate. Four flotation strategies: pre-decarbonization flotation, non-decarbonization flotation, rapid flotation, and enhanced rapid flotation are comparatively investigated. Flotation proves effective for gold recovery, with enhanced rapid flotation achieving optimal performance: a gold recovery rate of 86.89% and a concentrate grade of 12.95 g/t. In industrial design practice, a hybrid configuration combining Jameson flotation cells with conventional mechanically agitated flotation cells is implemented, achieving energy efficiency and floor space reduction.