Abstract: The Shangwei rock mass in Southern Jiangxi is located in the southern segment of the Taoshan-Zhuguang Uranium Metallogenic Belt, adjacent to the Xiazhuang Uranium Ore Field, and exhibits favorable geological conditions for uranium mineralization. This paper systematically analyzes the geological background, uranium source, heat source, fault structures, subsidiary dikes, hydrothermal alteration, and radiogeophysical anomalies of the rock mass, summarizing the spatial distribution characteristics and ore-controlling factors of uranium mineralization. The research indicates that uranium mineralization in the area is primarily controlled by the NE-trending Mashishan Silicified Fault Zone and its derived NNE-trending cataclastic alteration zones. Late Yanshanian intermediate-basic to acidic dikes provide both thermal energy and mineralizing fluids for uranium enrichment. Based on prospecting indicators, three key areas——Tianxin, Xiashe, and Shanghu——are proposed for further exploration, offering guidance for uranium prospecting breakthroughs in the region.