Abstract: The Kalatongke deposit in the Central Asian Orogenic Belt is a large Cu-Ni sulfide deposit hosted by several magfic intrusions in northern Xinjiang, China. The latest research results of the Kalatongke Cu-Ni sulfide deposit are systematically summarized according to tectonic setting, geochemical characteristics, magma evolution and sulfide mineralization. It shows that the Kalatongke intrusions and deposits formed in Early Permian, the Kalatongke intrusions can be explained by slab window magmatism, sulfide saturation in the magmas may be related to olivine crystallization and contamination with high Si crustal materials, and sulfide ores are consistent with flow concentration and/or gravitational settling of sulfide liquid.