Abstract: In order to provide a scientific evidence for quartz sand processed in glass industry in Huangdan, Muchuan County of Sichuan, based on the characteristics that harmful impurities Fe₂O₃ mainly occurred in ore as pyrite fine particles, flotation of iron purification experiments were conducted on a variety of flotation plans. The results show that the anti-flotation of iron purification method used in collector (ethyl xanthate:butyl xanthate=4:1) could achieve a significant effect on the comprehensive purification. The optimizing process parameters are:pulp pH=5, density 20%, the dose of collector 200g/t, flotation time 15min, the dose of frother 2^# oil 75g/t. Through the optimal process parameters, the standard quartz sand used in float glass industry could be processed:SiO₂ 98.882 t%,Al₂O₃ 0.520 t%,Fe₂O₃ 0.030 t%.