Abstract: Grey system theory was introduced into the research of coal mine safety input in this paper, safety input structure of a certain coal mine was analyzed and optimized by applying grey relational analysis method and weighted grey relational analysis method,the influence in sequence of each partial safety input on the safety benefit was acquired.The above two methods was contrasted according to intuitive analysis results,it shows that weighted grey relational analysis method is more suitable for practical engineering application.Analysis and optimization of safety input structure can provide quantitative basis for reasonable distribution of safety investment in coal mine enterprises,which has great significance for guiding scientific decision-making,improving safety benefit and achieving optimal enterprise benefit.