Abstract: It is imposible to get rid of the mining waste with the normal disposal way entirely.The only way for wasteless mining is to digest and to utilize its waste in the mining process.At the first,the paper introduces the importance to applying imitate biology group system and its principle and its way for design.Then entire design was made for several kinds of waste at Xinhui Gold mine,based on biology food chain and the mine's production process:the bigger graininess for tailings is used to fill stope with cement,and the smaller one is used to fill stope with non-cement;the bigger grain for mining waste is used for constructional materials,and the smaller one is used for pavement materials,after sifted and crashed;lead and zinc are extracted from the leaching residue,and its residue become a useful FS production by flotation process.The waste due to the mine production is digested and is utilized entirely and systematically,through three years trial and practice,wasteless mining is realized,from which,4100t lead and zinc,16500t FS product,and 35000 m³ constructional materials are obtained every year,its economical profit and social benefit is obvious.