Abstract: The paper is to ineroduce the advantage of hole-by-hole firing sequence and application of Orica high accuracy non-electric detonator in Dalian Limestone Mine.The paper also analyzed the data of comparison,introduced on-site measured vibration rcduction cffect.lt shows that holc-by-hole firing sequence can improve blasting result,reduce vibration,optimize total process cost and improve safety in operation to a great extern.