Abstract: Kunlun River area is located in the western part of the East Kunlun metallogenic belt,its mineral exploration work has just started.In this paper,tungsten-tin mineralization law of the Kunlun River region is summarized,geochronology and geochemistry of the ore-bearing granite are analyzed,the results show the ganite has the age of(396.8±4.0)Ma,which belongs to peraluminous calc-alkaline,syncollisional intrusive rocks.According to geochronology,geochemistry characteristics of the granite and tungsten-tin mineralization features in Kunlun River region,that the Early Devonian granite plays essential part for tungsten and tin mineralization,probably due to the collision of Bayan Har block and East Kunlun block.Combined with the results of exploration works in area,we believe a great prospecting potential for tungsten tin mineral.