Abstract: With Chinese characteristics,economic responsibility audit is a way of comprehensive analysis and judgment of the situation that administration directors perform economic responsibility and a high level of economic supervision means.Through systematical research of national guidelines on leaders' economic responsibility audit regulations,the economic responsibility audit work are discussed in this paper.Combing with practical,about economic responsibility auditing of main administrative leadership in geological exploration units,main content of the seven aspects and three influence factors aspects should be considered are put forward in this paper while audit results are discussed.These points not only provide the basis for appoint and preferment of directors,but also exert pressures on the undisclosed directors.By this way,the corruption is curbed at the origin with problem found in time by audit.