Abstract: Based on the study of the properties of a micro-grained dissemination magnetite ore in Qinghai province and the analysis and comparison of experiments, the experimental research of the beneficiation flowsheet was made, namely the flowsheet consisting of staged grinding and low intensity magnetic separation and anionic reverse flotation, which obtained concentrates having 62.82% grade and 59.84% recovery. And provided the basis of development and use of the iron ore resources in this region which have a better economic and social benefits.