Abstract: From the point of view of circular economy，in-situ leaching of uranium is introduced.Then，from the leaching method and deposit “appropriate matching”，“reduction” of leaching technology，microbial leaching technology，uranium and rhenium comprehensive recovery technology，technological innovation measures of circular economy and application results in Xinjiang in-situ leaching uranium mining are setted out.In the end of the paper，the characteristics of recycling economy of Xinjiang in-situ leaching which is characterized by “low consumption，high utilization and comprehensive recovery” are summarized.