Abstract: As salt minerals are easily dissolved in water,solution mining method is commonly adopted for salt minerals mining.Water inrush is more common during the mining,affects the production process,destroys the environment of groundwater and poses a threat to resident drinking water security.At present,the research of solution mining in rock salt mining area mainly focus on theories and methods rather than genesis analysis of water inrush.In this background,the author surveys and analyzes a water inrush of rock-salt mine in south area and consults genesis analysis of accidents in some related research fields,then summarized four factors affecting water inrush in rock salt mining area including stability of cavern,geological factors,engineering factors and corrosion factors.Through analyzing the logical relationship between the single factors during early exploitation,summarizing four kinds of evoked response chain analysis methods,building multilevel analysis system, "single factor analysis→evoked response chain analysis→comprehensive analysis",towards genesis analysis of water inrush in rock salt mining area.In this paper,the system is used to comprehensively analyze the cause of water inrush in salt mining area in the south of China,expecting to enrich the analysis systems and provide reference for solving such problems in other salt mine area at the same time.