Abstract: Taking Yuanjiang nickel ore area of Yunnan province as the research area.Based upon the preliminary analysis and processing to the engineering drilling data of mining area,and the use of Geo-statistical method to test and analyze the grade of ore bodies and thickness,seeking after the regularity of space distribution.Combining with the spatial data management and analysis function of GIS,industrial mineral ore amount of mineral resources and the metal quantity of the study area is estimated.finally,the research results are analyzed and verified by comparing the results with mining area reserves verification,which shows that the solid mineral resources reserves are estimated by using the method combining Geo-statistics and GIS,the results consistent with solid mineral resources reserves verification results,the variation no more than 5%.Therefore,the research on the method could provide the technologic support for the Department of Mine Production,the Department of Land and Resources.