Abstract: Mineral processing experiments were carried out on a refractory copper oxide ore,which has high oxidation rate,high ore slime content and high alkaline gangue content.We determine the best separation conditions and regime of agent for this copper oxide ore.The grade of copper concentrate reached 18.28%,the recovery of copper concentrate is 81.09% which has a great increase from 75%.The process fare simple and practicable,and it has industrial application value.