Abstract: Characteristics of mineral mineralogy were analyzed in this paper: floatability discrepancy of the same metallic minerals becoming larger while metallic minerals of the raw ore increasing. Flotation copper first process was used in this paper. Combined agent which is arsenic minerals restrained and copper mineral collecting agent were used to separate Cu and As. Copper concentrate in which copper grade is 21.10%, recovery of copper is 83.95%, content of As is 0.838% was gained.