Abstract: The geological prospecting work is weak in Qinghai province, so it is necessary to strengthen the study of metallogenic regularity and ore-controlling Factors. The metallogenic epoch is Precambrian, Caledonian, Hercynian, Indosinian,Yanshanian and Himalayan period, and the Caledonian and Indosinian period is main mineralization period. The tectonic environments of mineralization include Paleocrystalized basement, orogenic belt, oceanic crust sedimentary belt, continental rift system, oceanic crust subduction (trench), island arc, back-arc basin and continental margin active belt. Therefore, the main Ore-controlling Factors are lithosphere structure, tectonic-sedimentary environment, strata, lithology, lithofacies and transfer zone.