Abstract: It was analyzed that the characteristic of stratum configuration,geochemistry,mineral composition and chemic component,hydrogeology and hydrogeochemistry in the southern of Shihongtan uranium deposit.The characteristic of leaching uranium in the area as fellow:there are stable top and bottom aquifuge in the aquifer,but there are aquitard or impervious in the aquifer,so the aquifer is discontinuity.Uraninite is primary mineral and intimate intergrowth with pyrite and calcite.There are lower SiO₂ but higher Al₂O₃,CaO,Fe₂O₃ content in mineral.The hexavalent uranium is few but the tetravalent is more in uranium mineral.The total dissolve solid in groundwater is higher than demand of leaching,because the saturation index of CaSO₄ and CaCO₃ more than 0.The characteristics of leaching imply that it is impossibility that natural and effectible leaching uranium not only acid leaching and also alkaline leaching.So,ameliorating condition and technology of leaching uranium are necessary.