Abstract: Slope landslide stability in one open pit mine has been studied, the reinforcement scheme is put up that clearing up slope -undercutting slope-spraying anchor mesh-prestressing long anchor- drainage system, technology parameters of the scheme are optimized.With the slope stability analysis software SLOPE, the factors of safety are calculated and with the explicit finite difference method (FLAC), plastic region, displacement field, stress field, unbalance force of the excavated rock slope and of the reinforcement slope are analyzed. It is indicated that the reinforcement scheme will ensure the slope stabilization completely.