Abstract: During the prospecting and production of insitu leaching mining of uranium,the evaluation of reasonable index of geology and hydrogeology is a very important work.This paper analyzes the factors of geology and hydrogeology from the technique and economy of in-situ leaching of uranium,and discusses the principlses and methods to determine reasonable index of geology and hydrogeology.By adopting economy evaluations and price methods,the reasonable index of geology and hydrogeology on some deposit in the Yili basin of Xinjiang were brought forword.