Abstract: The combination of a new type collector DMF-1has been realized based on the collecting performances of sodium oleate,sodium lauryl sulfate,and DES type collectors.The experimental results shown that DMF-1was an effective collector for Chaoyang phosphate ore.At the optimum conditions of grinding fineness-0.074mm46%,pulp pH 7.00,slurry temperature 30.0℃,DMF-1 200g/t and sodium silicate 400g/t,through the open-circuit of one roughing-three cleaning-one scavenging obtained the concentration grade of 36.46%,recovery of 53.33% respectively,while the grade of tilling was 0.21%. Combining the results of the actual ores flotation,the mechanism and synergistic effect between the minerals and the collector DMF-1have been analyzed.The research shows that sodium lauryl sulfate acts as the frother,sodium oleate has hydrophobic and collecting performances due to chemical adsorption on the surface of apatite,and DES improves the property of DMF-1by the means of chemical and hydrogen bond adsorption.