Abstract: In recent years, the disruptive changes in the global oil and gas industry have had a profound impact on the development and strategies of international oil companies.The article starts from the analysis of coping strategies and main practices of four large international oil companies under the low oil price circumstance.By comparison of the experience, the different focuses for IOCs and NOCs respectively, the impact of strategic guidance on asset optimization and the tactics for assets with diverse nature are summarized.Finally, some proposals are given for how to realize the benefit development of Chinese petroleum enterprises under the current circumstances.