Abstract: The problems existing in the horizontal stratified consolidation method for a gold mine are introduced.Based on the optimization of mining methods and stope structure parameters optimization as the key research content, through indoor experiment, numerical simulation and theoretical analysis method, the safe, economic and broken orebody mining is researched.This paper makes a thorough investigation on a gold mine in Guizhou province.By combining the numerical simulation with the unascertained measure theory, determining the optimal mining method that is next to the deep hole mining is made between flat-back cut and fill method, this method can effectively solve the problems of the current mining, expand the mine production capacity, reduce the mining cost, improve mine economic benefit.According to the deep hole next to the characteristics of the ore is made between flat-back cut and fill method, mining experience and orebody characteristics, the numerical simulation software FLAC^3D stope structure parameters optimization research, finally it is concluded that width of stope structure parameters of stope is 4.5 m, height is 15 m or width is 5 m, height is 13 m, stope arranged along the strike, the length is 100 m.The results of this study have the important guiding significance to the field practice of the gold mine, and it can also provide theoretical basis for gold mining under the condition of “three soft”.