Goaf is an important hazard source that threatens mine safety, so the stability analysis, safety evaluation and management of goaf have become an important subject in mine research field at home and abroad.In this paper, based on the existing shape model data of the goaf in an open-pit mine, 3D Mine software is used to establish a three-dimensional engineering geological model with goaf in high-precision open-pit mine.FLAC^3Dand GEO-Slope softwares are used to conduct numerical simulation calculation and analyze the stability of open-pit slope by using limit equilibrium theory.The analysis results show that under the condition of occurrence of goaf, the tensile stress around goaf has reached 283 kPa, which will affect the stability of rock mass in a certain range.According to the displacement deformation rule of goaf, the local displacement deformation is obvious, but there is no overall displacement deformation of the open slope.The limit equilibrium safety factor F_sof typical section A-A and section B-B is greater than critical value of 1.2.The slope is in the optimal stable state and meets the safety requirements.According to the existing design scheme, with the development of open-pit mining, the goaf group has little influence on the slope stability.