In view of the large amount of metallurgical slag solid waste stored in Handan-Xingtai Area, experimental research on refining slag based cement with refining slag, blast furnace slag and desulfurization gypsum as the main components was carried out.The effects of refining slag content, cement sand ratio, concentration and temperature on the compressive strength of filling material are studied.XRD and TG-DTG are used to study the hydration products of refining slag and its preparation of cementitious materials.The results show that the hydration products of refining slag are mainly C₄AH₁₃, C₃AH₆, CH and gel.When the content of refining slag is 30%, slag is 46% and desulfurized gypsum is 24%, the compressive strength of the filled test block for 28 d is 7.35 MPa, the hydration products are mainly ettringite and C—S—H gel.By adjusting the concentration and cement sand ratio, the 28 d compressive strength of tailings filling material cemented by the refining slag can reach 1.09-8.73 MPa, which is up to 1.53 times that of cement filling material, meeting the strength requirements of filling bodies in different parts.When the temperature increases from 20 ℃ to 40 ℃, the early compressive strength of the filling body can be increased by 367% and 170% at 3 d and 7 d.The test results provide data support for the preparation of full tailings filling material with refining slag based cement, reduce the filling mining cost, and improve the utilization rate of refining slag resources.