Abstract: In order to study the influence of ore body retrieval in water-bearing mines on the stability of the roadway, 3Dmine-Rhion-Griddle-FLAC^3D coupling is used to construct a three-dimensional model of the mine area and to conduct a study on the change pattern of roadway deformation, stress and plastic zone during the ore body retrieval process. Conduct real-time monitoring and analysis of roadway deformation during mining to verify roadway stability. The results show that based on the 3Dmine-Rhino-Griddle-FLAC^3D analysis method, the stability of the roadway can be effectively analysed in the process of water-bearing mine orebody recovery, thus providing a theoretical basis for ensuring the stability of the roadway in the process of orebody recovery. After the end of ore body retrieval, the area with large amount of deformation is only in the location of the mining joint near the two horizontal roadways of the mining site, only the mining joint at the location directly above the mining site is affected by the disturbance, the amount of deformation is greater than 10 mm, the rest of the parts are disturbed relatively less, the amount of deformation is not more than 10 mm. During the ore body back mining process, the maximum compressive stress, maximum tensile stress and permeability pressure of the two horizontal roadways are subjected to exponential growth law with the increase of the back mining steps, the maximum compressive stress, maximum tensile stress force position corresponds to the deformation, the maximum value of the force is not more than the strength of the rock body, the permeability pressure of the larger areas are found in the location of the two helpers of each mining joint, the main roadway far from the location of the mining site, the permeability pressure basically maintains the initial permeability pressure state. Due to the existence of osmotic pressure, although the stress on the roadway at the two levels don’t exceed the rock strength, a small range of plastic damage occurs at the corner of the roadway and the end of the mining joint, indicating that the osmotic pressure has a weakening effect on the rock strength. The simulation results provide a theoretical basis for water-bearing mine stability mining.