Abstract: Tajikistan is one of the first countries to sign an intergovernmental cooperation document with China under the framework of “the Belt and Road” initiative and is our friendly neighbors.In aspect of geology, Tajikistan is in the Paleo-Asian metallogenic domain, rich in mineral resources such as gold, silver, lead, zinc, antimony, rare metals and others, but the degree of mining development is low and the market has great potential.In this paper, the present situation of exploitation and utilization of major mineral resources in Tajikistan is introduced together with degree of geological work, favorable and unfavorable factors for mining investment is analyzed.Suggestions are put forward to support Chinese enterprises’ mining investment in Tajikistan.The conclusion is that Tajikistan is rich in mineral resources such as gold, silver, lead-zinc, and antimony, and has considerable potential for rare metals.It is a favourable choice for Chinese enterprises to develop international mining cooperation in the future.Suggestions are given to Chinese enterprises that compare development goals and enhance cooperation enthusiasm of Tajikistan side, and fulfil social responsibilities and integrate into local society, and raise insurance awareness and avoid risks, and use media resources to build image.