Abstract: In order to improve the capacity of ore production block in Lilou iron mine, reduce production costs and reduce recovery time, we designed a multi-row medium-length hole one-time detonation scheme for experimental research.By designing the appropriate charging parameters, six rows of medium-length hole were successfully blasted at one time, good blasting results were obtained and explosive unit consumption was reduced.After repeated tests, the test was successful and can be widely used in the whole mine.